Study of choroidal neovascularization and its outcome after anti-vegf treatment


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Article type :

Original Article

Author :

Richa Gour

Volume :

5

Issue :

4

Abstract :

Aim: To evaluate the visual outcome and clinical response in CNVM patient after Anti-VEGF treatment. Material and Methods: This prospective observational study was conducted on 38 diagnosed eye of CNVM and its presence was confirmed by FFA. Complete ocular examination was conducted with respect to CNVM. They were followed up post injection (inj.ranibizumab) at day 1,7,1 month and on PRN basis, change in visual acuity and OCT findings was recorded. Results: Mean age of study participants were 62.215.9. Majority (63.3%) of the patients were more than 60 years of age. Out of 30 patients 18 were males and 12 were females with M: F ratio 6:4. Difference in visual acuity at pre and post treatment was significant with p value ( difference was found between pre and post treatment macular thickness on OCT (p value Conclusion: Intravitreal ranibizumab injection was beneficial treatment for all type of CNVM administered on PRN basis over 18 month of follow-up achieved stabilization of vision with significant improvement in BCVA and decreased retinal thickness by OCT.

Keyword :

 Optical coherence tomography (OCT), Fundus fluorescence angiography (FFA), Prorenata (PRN).