Differences in sympathetic activity in normotensive, prehypertensive and hypertensive individuals


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Article type :

Original Article

Author :

Arun Kumar. B, Nirmala N

Volume :

5

Issue :

4

Abstract :

Introduction: Hypertension is a major health hazard which at a later stage might lead onto various cardiovascular complications. Prehypertension is a precursor of Stage-I hypertension. Thus, the present study was done to assess the sympathetic activity in normotensive, prehypertensive and hypertensive individuals. Aims and Objectives: To compare the differences in sympathetic activity in normotensive, prehypertensive and hypertensive individuals. Materials and Methods: The study was conducted on 30 normotensive, 30 prehypertensive and 30 hypertensive subjects. Autonomic function tests were recorded using the instrument Physiopac-PP4, Medicaid system, Chandigarh. The following sympathetic function tests were performed: 1. Blood pressure response to standing, 2. Cold pressor test, 3. Isometric handgrip test. Results: Our findings on hypertensives showed that there is sympathetic dysfunction and on prehypertensives showed that there is sympathetic overactivity. Conclusion: Autonomic function tests can be used as a routine screening test to predict the future risk of hypertension at an earlier stage and also for a better prognosis during treatment.

Keyword :

Hypertensive, Prehypertensive, Autonomic function tests, Sympathetic dysfunction, Sympathetic overactivity.