Abstract :
Introduction: Gestational Diabetes Mellitus is defined as carbohydrate intolerance of variable severity with onset or first recognition during pregnancy. Recently it has been discovered that vitamin D plays a major role in glucose homeostasis. Studies have also reported that vitamin D deficiency may increase the risk of GDM.
Aim: To assess the maternal vitamin D status in women with GDM and to compare the levels of vitamin D in women with GDM and normal pregnancy.
Materials and Method: A total of 100 pregnant women during 24 to 28 weeks of pregnancy between the age group of 20 to 35 years and BMI of 18.5 to 29.99 kg/m2 were selected. Fifty women diagnosed having GDM by 75 gm OGTT with the blood sugar levels of > 140 mg/dl after 2 hours of oral glucose according to WHO criteria were taken as GDM group and 50 women with normal OGTT values as control group. The total Serum 25(OH)D levels were estimated by fully automated chemi luminescence immunoassay. The results were analyzed by chi square test and Student’s ‘t’ test. A p value of
Keyword :
Gestational Diabetes Mellitus, Vitamin D, Oral Glucose Tolerance Test, Chemi luminescence Immunoassay