Comparison of intrathecal Tramadol and Magnesium sulfate as an adjuvant to Levobupivacaine in mild Pre-eclamptic parturients undergoing caesarean section A prospective randomized control study


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Article type :

Original Article

Author :

Aditi A Dhimar, Vallary Modh, M R Upadhyay

Volume :

6

Issue :

4

Abstract :

Aims and Objective: Spinal anaesthesia is advantageous as compare to general anaesthesia for cesarean section especially in preeclampsia as it avoids the complications of general anaesthesia. To improve the quality of sensory and motor blockade and prolong the duration of postoperative analgesia, we had used tramadol and magnesium sulfate intrathecally with the primary aim to assess sensory and motor blockade and postoperative analgesia. Material and Methods: This prospective randomized control study included sixty preeclamptic parturient having more than 36 weeks of pregnancy with controlled hypertension aged 18-40 years with single pregnancy, planned for caesarean section of ASAPS II, III and able to understand VAS score were included. Parturients were randomly assigned to g roup LT (injection Levobupivacaine 0.5%, 1.5ml injection Tramadol 25 mg,0.5ml) and group LM (injection Levobupivacaine 0.5%, 1.5ml injection Magnesium sulfate 100 mg,0.5ml) using computer generated random numbers and the assignment was sealed in envelopes for concealment. They were assessed for sensory blockade, motor blockade and postoperative analgesia. Results: The onset of sensory block was late in group LM [102sec (102-105) sec] in comparison to group LT [69sec (66-72) sec, P 2) min] in comparison to group LT [1.6min (1.5-1.6) min, P in group LM [93.5sec (92-95) sec] compared to group LT [60sec (58-63) sec, P of post-operative analgesia was extended further for group LM [570min (540-600) min], in comparison to group LT [357min (342-360) min, P Conclusion: Intrathecal magnesium sulfate can be considered as a desirable adjuvant to Levobupivacaine in mild preeclamptic parturients undergoing cesarean section compared to tramadol.

Keyword :

 Intrathecal, Levobupivacaine, Magnesium sulfate, Preeclampsia, Tramadol.