A prospective double blinded study on effect of intrathecal dexmedetomidine as adjuvant to hyperbaric bupivacaine on onset and duration of subarachnoid blockade


Article PDF :

Veiw Full Text PDF

Article type :

Original Article

Author :

Sudhanshu Gupta, Abha Gupta, Brahma Pada Sarkar

Volume :

3

Issue :

4

Abstract :

Objective: To study the effect of low dose intrathecal dexmedetomidine as adjuvant to hyperbaric Bupivacaine in relation to onset & duration of sensory & motor block. Material and Methods: In the present double blinded prospective, randomized controlled trial study, we have aimed to compare the  two groups of  ASA –grade I patients divided in two groups i.e., group B - Bupivacaine 2.5ml (12.5 mg) alone (control group) and group BD - Bupivacaine 2.5 ml (12.5 mg) combined with Dexmedetomidine 5 ?g undergoing lower abdominal and lower limb surgeries to evaluate whether there is any clinching evidence of augmentation of motor and sensory block by addition of low dose dexmedetomidine (5?g). Results: Among both the groups, mean time to achieve onset of sensory & motor blockade was found to be not statistically significant (P>0.05). The duration of sensory block observed in group BD was 143.6±12.74 in contrast to group B 107±9.74. The difference in mean duration of analgesia between group B vs. BD, is statistically significant (P

Keyword :

Dexmedetomidine, Hyperbaric Bupivacaine, Sub arachnoid block