Abstract :
An artificial feature in tissue sections that is self-colored and unrelated is called an artefact. This has been an age long cause of misinterpretation that leads to misdiagnosis. It can result in alteration of normal morphologic and cytologic features that may occur as a result of the way the tissue has been handled, right from the time the biopsy, which is surgically obtained till the entire histopathological procedures of fixation, processing, embedding, sectioning and staining are performed on it. This article reviews the common artefacts encountered during tissue processing.
Keyword :
Artefact, tissue processing, diagnosis