Epidemiology and phenotype variation in young diabetes patients


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Article type :

Original Article

Author :

Shivani Arya, Dharmendra Panchal, Banshi Saboo

Volume :

3

Issue :

3

Abstract :

Introduction: More and more people are diagnosed with type 2 diabetes at a younger age nowadays. It is need of an hour to study epidemiology and phenotype variations in this group. Aims: To study phenotype among the young diabetes population. Materials and Methods: We retrospectively analysed data of all type 2 diabetes patients attending OPD from Jan 2019 to march 2019. Total 106 patients attended OPD during this period. BMI, PBF (% BODY FAT), VFI (Visceral fat index), Hba1c, Triglyceride, LDL and NON HDL, Total Calorie intake and % daily carbohydrate intake were reviewed for all 106 patients. All 106 subjects were divided in two groups based on their age; group A age 40 years (n=33), group B age > 40 years (n=73). Group B was further divided into group B1 (age 41-60 years) (n=58) and group B2 (age 61 year) (n=15). Average of BMI, Body fat analysis and biochemical parameters were compared between these two groups. Student’s T test was used to calculate the p value for all parameters. Results: We analysed data of all 106 patients and average of BMI, PBF, VFI, HbA1c, TG, LDL, NON HDL, TOTAL CALORIES, % Carbohydrate was compared between Group A and Group B. Average TG, LDL, NON HDL and % daily carbohydrate intake were higher in group A as compared to total as well as group B. out of this all parameters NON HDL and % of daily carbohydrate intake was higher in group A as compared to group B [(NON HDL (p value 0.0412); % carbohydrate intake (p value 0.064)]. In sub analysis the difference was more significant in group B2 (NON HDL) p value 0.0118; % of carbohydrate intake (p value 0.0275). Conclusion: NON HDL level and % of daily carbohydrate intake are significantly associated with a young Type 2 diabetes population ( 40 years) as compared to the adult population particularly type 2 diabetes population with age 60 years. NON HDL cholesterol and % of daily carbohydrate intake can be more easy targets to reduce prevalence of type 2 diabetes in the younger population. However, it may require further research in mass population.

Keyword :

 Diabetes in young phenotypes in diabetes risk factore of diabetes in young carbohydrates intake non HDL and young onset diabetes.