Secretory carcinoma of breast: No more a juvenile tumor


Article PDF :

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Article type :

Case Report

Author :

Swati Smita Sahoo, Deepika Mishra, Meenakshi Mohapatro*, Milan Tripathy, Prasant Kumar Das, Fakir Charan Munda, Shushruta Mohanty, Alkananda Balbantray

Volume :

8

Issue :

3

Abstract :

Introduction: Secretory breast carcinoma (SBC) is one of the rare breast neoplasm with an incidence rate of < 0> Case Presentation: A 45 -year-old female presented with palpable lump in left breast. FNAC was suggestive of mucinous carcinoma. The diagnosis of SBC was made through histopathology and Immunohistochemistry Discussion : Recent study report suggested that the disease may also occur at a later age group in contrast to the conventional thought of onset at juvenile age group. Long-term survival is good for these cases. In radiological studies of breast imaging it mimics a benign tumour Immuno-histochemistry and cytogenetic are of the tumour are the ancillary investigations for confirmation of diagnosis. Conclusion : Although rare diagnosis of SBC can be confirmed by histopathological studies and IHC. It is slowly progressive but has a good prognosis.  

Keyword :

Secretory breast cancer (SBC), Immunohistochemistry, Balanced translocation t (12, 15), ETV6-NTRK3 Gene fusion.