Abstract :
Background: Orthodontic tooth movement following application of force features bone remodelling changes in periodontal and dental tissues. These necessary orthodontic tooth movement achieved by numerous orthodontic procedures that evokes pain sensations in patients, such as separator placement, archwire placement and activations.
Objective: The aim of the study is to compare the levels of interleukin 1-beta and prostaglandin E2 in GCF with pain perception after placement of elastomeric separators with and without low level laser therapy.
Materials and Methods: 12 patients scheduled for orthodontic treatment, were screened test and control. Mesial and distal elastomeric separators flanked the maxillary first molar arch. The experimental side received 20s of Ga Al As, diode laser irradiation at 810 nm, 2 J/cm2, 200 mW power output, while the control tooth did not. GCF was collected from the mesiobuccal and mesiopalatal sides of first molars in the maxillary quadrant before, 1hr, 24 hours, and 48 hours after separator installation from both groups to quantify IL1-b and PGE2.
Result: The control and experimental group had IL-1β levels of 18.609 ng/ml (SD = 3.833) and 17.582 ng/ml (SD = 2.425) at the 'Before' time point, with p< 0 xss=removed xss=removed xss=removed xss=removed xss=removed xss=removed>
Conclusion: Low-level laser therapy has been shown to reduce pain perception and decrease inflammatory mediators IL-1β and PGE2 in GCF patients with elastomeric separators. A positive correlation exists between these biomarkers, pain perception, and laser irradiation across all time intervals.
Keyword :
Low level laser therapy, Visual Analog Scale, Interleukin, Prostaglandin