Abstract :
Objective: As there are wide differentials for longitudinally extensive transverse myelitis (LETM), its aetiology should be found to optimise therapy.
Aims: Clinical profile of LETM.
Settings and Design: ambispective observational study.
Methods and Materials: 73 patients with acute to subacute myelitis involving 3 or more vertebral segments were properly investigated.
Statistical analysis used: Student t test and Mann-whitney test used, and comparison of data done using SPSS version 22.0
Result: The etiology found were in form of neuromyelitis optica spectrum disorder (NMO-SD) in 18(24.6%), para-infectious in 13(17.8%), idiopathic in 17(23.2%), infectious in 9(12.3%), and rest were acute disseminated encephalomyelitis (ADEM), subacute combined degeneration (SACD), infarct, radiation myelitis etc.
Conclusions: It is important to find etiology of LETM to optimise the therapy as the in inflammatory myelitis other than NMOSD, the line of management differs. Relapsing nature of some myelitides is an important aspect in management
Keyword :
Longitudinally Extensive Transverse Myelitis, Neuro-myelitis Optica Spectrum Disorders, Acute disseminated encephalo-myelitis, Subacute combined degeneration