Abstract :
Background: The transformative journey of Platelet-rich plasma, fueled by discovery of Platelet-Derived Growth Factor (PDGF), underscores its regenerative potential. This comprehensive exploration delves into fundamental characteristics and applications with a focus on its growing prominence in dermatology and aesthetics.
Materials and Methods: An open labelled interventional study was conducted at a tertiary health care centre in Western India to assess the efficacy and safety of PRP in various indications that mainly included patterned hair loss, post traumatic scars, acne scars, melasma and striae distensae. Patients were included in the study based on pre-determined inclusion and exclusion criteria. 6 sessions of PRP were conducted and response to therapy was evaluated using standard objective and subjective scores.
Results: The study included 60% female cases with most patients in the age group of 31-40 years (51.2%). For patterned hair loss, the mean change in hair count at end of therapy was significantly greater for baseline to final (P < 0>
Conclusion: The study's results, while acknowledging certain limitations, emphasize PRP's potential efficacy in diverse dermatological conditions. The study underscores the correlation between dermatological conditions and treatment outcomes, highlighting the positive impact of PRP therapy.
Keyword :
PlateletRich Plasma, PlateletDerived Growth Factor, Patterned hair loss, Vancouver scar scale, Goodman & Baron's quantitative scar scale