Study of P-wave dispersion in patients of psoriasis: An observational study


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Article type :

Original Article

Author :

Ujjwal Kumar, Meetesh Agrawal, Krishnendra Varma, Aishwarya Mahadik, Shashank Bhargava, Dhruv Mishra*

Volume :

9

Issue :

2

Abstract :

Background: Psoriasis being a multisystemic disorder has multiple systemic comorbidities apart from cutaneous manifestations including metabolic syndrome and cardiovascular diseases. Aim: To study P-wave dispersion in patients of psoriasis. Materials and Methods: A total of 71 patients who presented in the dermatology OPD with chronic plaque psoriasis were assessed for disease severity and their ECG was evaluated. Results: In this study of 71 patients aged 15-60 years, a strong positive correlation was found between PASI score and P-wave dispersion (r=0.703, p=0.000) indicating a strong association between disease severity of psoriasis and development of cardiovascular diseases. Conclusion: The P-wave dispersion was significantly higher in patients with high PASI scores. This indicates that the patients of psoriasis are at a higher risk of developing cardiovascular diseases like atrial fibrillation.  

Keyword :

Psoriasis, Cardiovascular diseases, Metabolic syndrome, ECG, P­wave dispersion, Atrial fibrillation