Abstract :
Introduction: Melasma is one of the common hyper pigmentation disorders presenting with symmetrical
brownish black patches on sun-exposed areas. Many studies have been conducted to determine the
relationship between Melasma and thyroid autoimmunity.
Aims and objectives: to evaluate the relationship between thyroid profile and Melasma patients
Materials and Methods: A case control study was carried out evaluating thyroid status (serum T3, T4 and
TSH) in 50 patients with Melasma and 50 individuals without Melasma. Statistical analysis was done.
Results: a total of 100 patients including both men and women were enrolled in the study. The age group
was 20-50 years. The F: M ratio was 7:1 in both cases and controls. Five (5) patients in the Melasma group
and three (3) patients in the control group showed hypothyroidism.
Conclusion: There is a suspicion in associating Melasma and thyroid disorders.
Keyword :
Melasma hypothyroidism autoimmunity thyroid function tests, Thyroid stimulating hormone.