Abstract :
Background: Phyllodes tumors being a rare neoplasm of the breast attributes only 0.3% to 1% of all breast tumors, with an annual incidence of about 2 per million women. Malignant differentiation of phyllodes tumors can occur, resulting in cases of extremely rare heterologous sarcomatous differentiation.
Case Report: We present a rare case of a 63-year-old women with features of malignant phyllodes with sarcomatous (chondrosarcomatous) differentiation.
Conclusion: Morphologically, phyllodes tumors are categorized as benign, borderline and malignant based on the scope of stromal atypia, mitotic activity, stromal overgrowth, and the tumor margins. The presence of heterologous elements in a phyllodes directly upgrades it to a malignant category. A close follow-up with a CT scan is of utmost need to detect the recurrence and metastasis to the earliest.
Keyword :
Phyllodes tumors, Chondrosarcoma, Malignant phyllodes, Recurrence, Metastasis.