Abstract :
Introduction: Cancers of the kidney amount to 2% of total human cancer burden, with approximately
1,90,000 new cases diagnosed each year. Prognostic markers for RCC, such as tumor stage, grade, necrosis
or microvascular invasion are important in determining appropriate follow up and selecting patients for
adjuvant therapy.
Aim: Aim of the study is to analyze the clinical and histopathological variables in Renal Cell Carcinoma
and establish possible correlations between them, if any. The study also highlights a rare case of mucinous
tubular and spindle cell carcinoma of the kidney.
Materials and Methods: This is a retrospective study involving 52 cases of Renal Cell tumors diagnosed,
during period of 2 years (2015-2016)
Results: Clear cell, Papillary, Chromophobe Carcinomas and Oncocytomas accounted for 78.85%, 7.69%,
1.92% and 7.69% of all cases, respectively.
Conclusion: Clear cell Carcinoma was the most common histological type, followed by Papillary
Carcinoma. Majority of Clear cell Carcinomas were grade 2 with most common stage being PT1b. Tumour
necrosis was common in Papillary Carcinomas. We had one case of Mucinous Tubular and Spindle cell
Carcinoma which is a rare variant.
Keyword :
Histomorphology, Renal cell carcinomas.