Abstract :
Introduction: Diabetic (DR) is one of the long-term complications of Diabetes. Chronic hyperglycemia cause abnormalities to both retina and choroid. Optical coherence tomography (OCT) is a non-invasive imaging modality, which plays a vital role in revealing the and development of retinal– diseases.
Materials and Methods: This prospective observational study included 128 eyes of 64 subjects diagnosed with type 2 diabetes and out of 128 eyes, 113 (88%) eyes were found to have DR. Collected data included age, gender, duration of diabetes, control, comprehensive ocular examination, photography, and CT measurement on OCT.
Results: Mean age in the study group was 53.71 ± 9.37 years (45–70 years). Out of 113 eyes, 19 (17%) eyes were diagnosed as mild NPDR, 21 (19%) eyes had moderate NPDR, 36 (31%) eyes had severe NPDR and 37 (33%) eyes had PDR. The average SFCT in MILD NPDR was 310 ± 14.70 at 95% CI (1.86), MODERATE NPDR was 316 ± 17.97 at 95% CI (2.70), SEVERE NPDR was 326.02 ± 14.05 at 95% CI (4.59) and PDR was 298.55 ± 18.75?m at 95% CI. (1.41). The presence of DME significantly affects average SFCT. It was observed that thickness tends to increase as the severity DR with DME progress.
Conclusions: The average SFCT was thicker in patients with increase in severity of DR, and then SFCT decreased in patients with PDR. As the severity of NPDR increased from mild to moderate to severe NPDR, there was increase in sub thickness. (p