Abstract :
Abstract Background: Despite the fact most of the medicinal plants can be associated with lowmortality, they can lead to severe morbidity such as stunted physical and mental growth, among childrenwhen used in treatment of gastrointestinal diseases such as diarrhoea. Native Americans used capsicumfruits for various conditions for centuries and the identification of bioactive compounds in these fruitsvindicates this practice. Finding among Capsicum frutescens, our study sought to establish if the plant hadantifungal or antioxidant properties on the basis of its bioactive metabolites.Methods: The fruits were first washed and then put in an oven at a temperature of 60?C for 48 hours untildried. They were then left to cool and later on a fine powder was made from it. The aqueous extract wasobtained after boiling 100mL distilled water with 10g powder at 15 minutes. The preparation of a samplein a heated injector block and then ongoing on the head of a chromatographic column packed with a non-volatile liquid phase is the technique called gas chromatography. The inhibitory zone diameter, inmillimeters (mm), is applied as a factor for the evaluation of the result of antifungal efficiency of thephenolic extracts.Results: Altogether, GC–MS revealed that Juniperus communis contains more than nineteen wishednatural and helpful secondary metabolites. This paper describes the anti-fungal and anti-yeast actions ofconventional antibiotics and three different ethanolic, methanolic, and ethyle acetate extracts of Juniperuscommunis fruits. Phytophthora infestans (16.09 ± 0.19, 13.26 ± 0.15, and 21.19 ± 0.24 respectively), P.oryzae (20.07 ± 0.23, 13.03 ± 0.15, and 23.11 ± 0.28 respectively), Microsporum canis (19.08 ± 0.22,15.37 ± 0.18, and 23.94 ± 0.28 respectively), and C. glabrata (13.83 ± 0.15, 21.19 ± 0.24, and 18.01 ±0.21 respectively). Posaconazole (PCZ) and Voriconazole (VCZ) as standard anti-fungal activity were(24.09 ± 0.29 and 29.36 ± 0.38) respectively. Capsicum frutescens metabolites was very highly activeagainst Microsporum canis (23.94 ± 0.28). Antioxidant activity (Superoxide radical scavenging andNitric oxide radical scavenging) of (methanol, Ethyl acetate, Ethanol extract and standards) of Capsicumfrutescens. recorded 19.60 ± 1.01, 23.76 ± 1.30, 26.36 ± 1.39 and Quercetin (standard) 39.82 ± 2.07respectively of Superoxide radical scavenging. 35.00±2.08, 46.51±2.93, 30.28±2.67 and Curcumin(standard) 83.12±4.07 respectively of Nitric oxide radical scavengingConclusion: Bell pepper extracts, like Capsicum frutescens, have antifungal properties against a fewfungal infections that cause food poisoning. There were determined to be biologically active substances,including alkaloids, flavonoids, polyphenols, and sterols. As a result, Capsicum fruits could be used infood and medicine as a natural antibiotic. This article provides insight into pepper's use and supports theuse of Capsicum fruit extracts for antifungal activity. The scientific basis for pepper's usage in cookingand traditional medicine should be strengthened by these findings.
Keyword :
Keywords: Capsicum frutescens, GC/MS, Antioxidant, Antifungal, Metabolites