Abstract :
Abstract Objective: Cardiovascular diseases represent the most serious complications in the patients with type 1 diabetes mellitus (DM). Endothelial dysfunction and increased aortic stiffness play role in the occurance of these disorders. Aim of this study is to evaluate the patients cardiac functions and aortic elasticity parameters in children with type 1 DM. Materials and methods: Thirty nine patients with type 1 DM and 39 controls were included in the study. After physical examination, cardiac evaluation was performed with conventional echocardiography, Doppler and tissue Doppler echocardiography. Aortic elasticty parameters were calculated. Results: Systolic blood pressure, mean arterial pressure (MAP), pulse pressure (PP) and heart rate (HR) were higher in the patients than controls (p0.05, for all). Aortic systolic and diastolic diameters and aortic elasticity parameters were similar with controls (p>0.05, for all). Echocardiographic parameters and aortic elasticity parameters were similar in the patients who were grouped according to hemoglobin A1c and duration of diabetes (p>0.05, for all). E wave velocity was positively related with PP, while E’/A’ was positively associated with HR and negatively associated with MAP and diastolic blood pressure (p
Keyword :
Keywords: Aortic stiffness, Children, Diastolic function, Type 1 diabetes