Abstract :
Solid dispersions are one of the most promising strategies to improve the oral bioavailability of poorly water
soluble drugs. By reducing drug particle size to the absolute minimum, and hence improving drug wettability,
solubility increases hence bioavailability may be significantly improved. They are usually presented as amorphous
products, mainly obtained by two major different methods, melting and solvent evaporation
KeyWords: Hot melt extrusion, Hyperlipidemia, Povidone, Eudragit RL, Eudragit RS, polyethylene glycol (PEG),
degree of porosity, Renex, Texafor AIP
Keyword :
Hot melt extrusion, Hyperlipidemia, Povidone, Eudragit RL, Eudragit RS, polyethylene glycol (PEG), degree of porosity, Renex, Texafor AIP