Panacea Journal of Medical Sciences

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IP Innovative Publication Pvt. Ltd.

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Indexed - 2021 : IPI Value (4.00)

Review of clinical presentation of children with celiac disease - A retrospective study

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Original Article

Author :

Sunil Pathak, Avinash Bothra, Manish Rasania, Dipika Bhil, Nimya Mary, Prerna Dogra

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Abstract :

Introduction: Celiac disease is a chronic immune mediated enteropathy, produced by the gluten ingestion in susceptible people, where gluten act as environmental trigger. Celiac disease has global prevalence of 1%. Its presentation ranges from simple anaemia, gastrointestinal manifestation, short stature to neurological manifestations. The high level of suspicion helps in prevention of chronic complications of the disease. Objective: To identify diverse clinical manifestations of children with celiac disease. Materials and Methods: Children with previously established or newly diagnosed celiac disease, during (2011-2019) were recruited. Data was collected retrospectively from medical records and clinical notes, and subsequently analysed. Result: The mean age was 7.90 years (3-15 years). 59.09% (13) patients were females. 90.90% (20) patients had gastrointestinal symptoms and anemia and 81.81% (18) had short stature. Other symptoms include lower-limb edema (1), seizure (1), dental caries (1), anasarca (1), abdominal Koch (1), rashes (1), lower limb weakness (1). Biopsy was positive in 7/8 patient. Conclusion: Knowledge of diverse clinical presentations will help in increased clinician’s awareness and high level of suspicion. It will enable an early diagnosis and management.  

Keyword :

Celiac disease, tTG- tissue transglutaminase, Anemia, short stature

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