ABO blood group relationship with COVID-19 occurrence and severity

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Original Article

Author :

Anurag Yadav*, Ravi D Mala, Sri Hari Yadav Besati, D Padmasree, Golla Anmol Manaswini, Nanda Kumar L G

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Abstract :

Objective: Study aimed to assess the relation between the ABO blood group and occurrence of COVID-19 and severity. Materials and Methods: This was a single centric retrospective study conducted at the MNR Medical College & Hospital among the patients admitted for COVID-19 infections during the July 25th to 30th October 2020. All the patients who were tested COVID-19 positive and the blood type recorded in the health care record were included in present study. The demographics, comorbidities, and the laboratory data of CBC, RBS, liver function test, renal function test, C-reactive protein, serum ferritin and D-dimmer were reviewed. Result: Total of 365 patients are enrolled in present study (53.2% male and 45.8% female. The blood group of A was common followed with blood group O and group B. 68.5% (n=250) of the patients included had turned to be positive for COVID-19 and 31.5% (n=115) were with negative COVID-19. There was a significant higher odds of the COVID-19 among the blood group A compared to the other blood group type and blood group O had lower odds of the disease. Requirement of ventilator support was significant higher in patients with group A compared to other blood group. In present study, total of 4 patients succumbed to death. Conclusion: There is presence of higher risk of type A blood group compared to other blood group type with susceptibility for the SARS-CoV (COVID-19) and also the severity of the progression of disease.

Keyword :

SARC­ CoV, COVID­ 19, Mortality, ABO, Blood group.
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