Abstract :
Background: Periapical pathosis is considered as a persistent microbial infection throughout the treatment period of root canal procedures. Recently the prevalence of endodontic failures is huge and this primarily accounts for the periapical pathogens; mainly Enterococcus faecalis and Candida albicans. Thus, with the advent of newer materials; identification of the most appropriate sealing material with highest antimicrobial efficacy is essential for endodontic success.
Aim and objectives: To evaluate and compare the antimicrobial efficacy of MTA Angelus, Biodentine and Theracal LC against Enterococcus faecalis and Candida albicans.
Materials and Methods: An in-vitro study was conducted using three silicate-based cements; MTA Angelus, Biodentine and Theracal LC. Their antimicrobial efficacy was evaluated using Tube dilution method and their Minimum inhibitory concentration (MIC) and Bacterial counts (CFU’s) were assessed and compared. Statistical analysis was done using Paired t-test and ANOVA at 95% confidence interval (p value
Results: The MIC was highest and CFU’s were lowest with Biodentine in comparison with other two materials. There were statistically significant differences noted between Biodentine and MTA angelus.
Conclusion: Our study results conclude that Biodentine was found to be more anti-bacterial as compared to MTA angelus and theracal LC.
Keyword :
Candida albicans, Enterococcus faecalis, Endodontic failure, Periapical pathosis, Tube dilution.