Abstract :
The incidence of nausea or vomiting changes much with etiopathogenesis. Multiple neurohumoural pathways lead to nausea and vomiting. The various classes of antiemetics target different pro-emetic pathways to alleviate nausea and vomiting. Some drugs target more than one pathway. It is demonstrated that combination therapy is more effective than single anti-emetic agent.
Keyword :
Vomiting, Chemoreceptor trigger zone, Aprepitant, Cannabinoid receptor agonist, 5 HT receptor antagonist, Neurokinin receptor antagonists.