Volume :
2
Issue :
4
Abstract :
A simple, rapid and sensitive method has been developed for the quantitative estimation of n in bulk and tablet. The wavelength 285 nm was selected for the estimation of drug using distilled water: acetonitrile (50:50) as a solvent. The drug obeyed Beer-lambert’s law over the concentration range 5-25mg/ml. The accuracy of the method was assessed by recovery studies and was found between 99.73-100.17%. The method was statistically validated for the linearity, precision, accuracy, repeatability, LOD, LOQ and ruggedness. The method was successfully applied for routine analysis of this drug in bulk and formulations.