Volume :
3
Issue :
1
Abstract :
Urinary tract infection continues to be an important public health problem worldwide in terms of both morbidity and mortality. Nowadays urinary pathogenic agents which were susceptible to common antibiotics became resistance and their number also increased gradually. It has been shown that with the development and widespread use of antimicrobial drugs, the types of the pathogenic organism and their antibiotic susceptibility have changed over time, making continuous and periodic surveillance necessarily in guiding appropriate antimicrobial therapy Therefore, this study was carried out to determine the bacterial profile and their antibiotic susceptibility pattern of patients with suspected cases of urinary tract infections in University of Gondar teaching hospital Northwest Ethiopia. A total of 975 urinary tract infections suspected patients were recruited for this study. Clean catch midstream urine was collected into sterile universal containers and were examined using culture. Of 975 urinary tract infections suspected patients, 250(25.6%) were positive for significant bacteriuria. Escherichia coli was the most predominant gram negative bacteria and Staphylococcus aureus from gram positive bacteria. All isolates of Gram negative bacteria and most Gram-positives (85.1%) isolates showed multiple drug resistance. Chloramphenicol (62.3%), ciprofloxacin (50.9%) and norfloxacin (50%) were effective drugs for Escherichia coli and ciprofloxacin (61.9%) and ampicilline and norfloxacin (57.1%) for Staphylococcus aureus compared to other tested drugs. The prevalence of bacteriuria was comparable to pervious similar study. However, most current isolates were resistant to multiple drugs and the effectiveness of most drugs like ciprofloxacin, amoxicillin, erythromycin were reduced.