Volume :
6
Issue :
3
Abstract :
The aim of this study was to formulate and evaluate microspheres of Ranitidine. These formulations are mainly usefull in inhibition of gastric acid secretion. It shows action on histamine stimulation and gastrin stimulated acid secretion. The compatability was first checked with FTIR spectrophotometric for drug and excipients. The prepared product was subjected to various studies like drug entrapment efficiency particle size, bulk density, % yield, % buoyancy, etc. The individual peaks of each drug and the excipients were compared and the compatibility was studied and this was done for all the formulations in the preparations.