Volume :
1
Issue :
3
Abstract :
The aim of the present investigation was to prepare delayed release i.e., enteric coated pellets of Rabeprazole sodium by using hydroxypropyl methyl cellulose based sub coating and methacrylic acid copolymer based enteric coating. The different batches of pellets were prepared by drug suspension layering method. Comparative study of dissolution profile of final batch with market preparations was conducted and it was concluded that final batch shown good similarity with market products. The results of the accelerated stability of final formulation for three months revealed that storage conditions were not found any significant changes in final formulation.