Abstract :
The existing study was designed to evaluate the ameliorative influences of Moringa oleifera on several immune parameters in male rats subsequent to lead administration. Twenty eight adult male rats were randomly assigned equally into 4 groups; control group was given distilled water. Lead treated rats were administrated a dose of 44 mg of lead acetate/kg BW. Moringa group was treated with 50 mg/ kg BW of Moringa oleifera leaf extract. Lead and moringa treated group was given a dose of 44 mg/kg of lead acetate and 50 mg/ kg of moringa extract. Treatments were given orally by gavage tube for one month. By the termination of the experimental period, rats were immolated; spleen and thymus weights were recorded in addition to the collection of blood and tissue samples. Tumor necrosis factor alpha (TNF-?), interferon gamma (IF-?), interlukin-2 (IL-2) and total antioxidant capacity (TAC) were assayed in serum. Complete blood picture was evaluated for rats. Body weight gain was reduced significantly (P
Keyword :
Rats; lead; Moringa; immunity