Abstract :
Low 25(OH) vitamin D concentration is observed to be associated with liver dysfunction and predict hepatic
decompensation and mortality in patients with chronic liver disease. The objectives of the study were to estimate serum
vitamin D levels in patients with chronic liver disease; to find out the severity of cirrhosis according to Child Pugh
Classification and to find out the relationship between severity of cirrhosis (Child Pugh) with levels of serum Vitamin D.
This cross sectional study was conducted amongst 100 patients presenting with cirrhosis of liver to OPD or admitted in a
tertiary care hospital during study period year 2017-2018. Details regarding socio-demographic variables and history were
obtained followed by physical and biochemical examination. Data was compiled using MS excel and analysed using Epi
Info 7.2 software. Majority of the patients were in the age group 41-60 years with male preponderance. Mean Vitamin D
level estimated in the study being 13.9±7.7 was highest in the Child Pugh ClassAand lowest in the Child Pugh Class C. The
association of meanVitaminDin relation to Child Pugh Class was found to be statistically significant (p
Keyword :
Cirrhosis, Child Pugh score,Vitamin D