Prevalence and treatment of malaria during the AIDS infection in hospital area of Bamako, Mali


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5

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1

Abstract :

Malaria and HIV are a major public health problem in developing countries. Our study was a prospective study to find the incidence of malaria during HIV infection in Bamako at the national referral and teaching hospital “Point G” from May 1st, 2006 to February 28th, 2007. Among 212 patients hospitalized or followed as patients with HIV positive by rapid tests: Immuno Comb II HIV 1/2 (Organics, Strasbourg, France) and genie II HIV 1/2 (Sanofi Diagnostics Pasteur, France); 46 patients had a positive malaria test (21.6%). Theses coinfected patients (Plasmodium/ HIV) have been enrolled in the study. The age average was 34.4 ± 9.4 years. The sex ratio was 0.7. The patient majority had a CD4 rate less than 200 cells/mm3. The HIV 1 infection was predominant in 45 patients (97.6%). The risk of exposure to the complicated malaria during HIV infection was higher in patients with the AIDS stage than seropositive patients (p = 0.04 fisher). The risk of exposure to moderate anemia during HIV infection was higher in patients with the AIDS stage than seropositive patients (p = 0.01 fisher). The majority of patients did not use preventive measures which are 71.7%. The hospital case lethality was 34%. We can confirm that Malaria has been relatively frequently during the HIV infection in Mali. Malaria chemoprophylaxy combined to bed nets use by HIV/AIDS patient should improve the morbidity and mortality due to this disease.
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