Abstract :
To describe the dermatological manifestations noted in multitransfused beta thalassemia major patients aged between two to twelve years and also to find out any correlation with their serum ferritine level, this study was done. A total 56 thalassemia children were examined for dermatological manifestatios and their serum ferritin levels were measured. Amongst the patients, male to female ratio was 1:1. Most of the study subjects belonged to the Muslim community (64.3%). Dermatological changes were found amongst 94.6% study children and were more frequently seen in females (96.4%). Children belonging to older age group showed increased frequency (100% in >8years) of dermatological changes. Xerosis and Hyperpigmentation were the two most common dermatological changes noted in 66.1% and 53.6% study subjects. Pityriasis versicolor and alba (12.5%), urticaria (5.4%), acanthosis nigricans (8.9%) were other common dermatological manifestation. Besides generalised hyperpigmentation, some subjects (12.1%) were foud to have isolated forehead hyperpigmentation. Less common dermatological changes noted were moluscum contagiosum, diffuse hair loss, nail brittleness, mucosal hyperpigmentation, freckles, acneform eruption, milliaria and pompholyx. The study showed there was a statistically significant correlation between urticaria and the level of serum ferritin(p
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