Indian Journal of Pharmacy and Pharmacology

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IP Innovative Publication Pvt. Ltd.

Indexed - 2016 : IPI Value (4.1)

Indexed - 2017 : IPI Value (3.22)

Indexed - 2018 : IPI Value (3.46)

Indexed - 2019 : IPI Value (3.50)

Evaluation of antidepressant effects of rosuvastatin in male albino mice by tail suspension model

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Original Article

Author :

Avanthi E1,*, Pradeep Kumar L.2

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Abstract :

Objective: To evaluate the antidepressant activity of Rosuvastatin in male albino mice. Method: Thirty male swiss albino mice were selected for tail suspension model. There were five groups and each group had six animals. The control group received Normal saline (10ml/kg I.P), the standard Imipramine (10mg/kg I.P), the 3 test group received Rosuvastatin (10mg/kg, 15mg/kg, 20mg/kg I.P) respectively. The test was conducted 30mins after injecting the drugs. Duration of immobility was noted. Statistical analysis was performed using Mean +/- SEM. One way ANOVA followed by Tukey’s post hoc test was done P

Keyword :

Rosuvastatin, Antidepressant, Albino mice

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