International Journal of Clinical Biochemistry and Research


Online-Issn No :
2394-6377
Print-Issn No :
2394-6369
Language :
English
Publisher :
IP Innovative Publication Pvt. Ltd.

Indexed - 2016 : IPI Value (4.04)

Indexed - 2017 : IPI Value (4.04)

Indexed - 2018 : IPI Value (4.06)

Indexed - 2019 : IPI Value (4.00)


Dendritic cells and vitamin D in dry eye disease


Article PDF :

Veiw Full Text PDF

Article type :

Original Article

Author :

Balakrishnan .M1 , K. Sumathi2,* , Pinky Karam3 , Rajarathinam4

Volume :

5

Issue :

3

Abstract :

To study the role of dendritic cells and vitamin D in troublesome evaporative dry eye diseases. Materials and Methods: This is a cross sectional study which includes 108 patients having evaporative dry eye disease and 86 normal healthy volunteers. Ocular surface index, Shirmer’s test and tear film break up time, corneal dendritic cell density, vitamin D and cytokines in serum/tear were estimated. Vitamin D, cytokine in serum/tear and corneal dendritic cell density were estimated. Result: Higher dendritic cell density noticed in evaporative dry eye disease patients compared to control group volunteers and revealed positive correlation with ocular surface index (P Conclusion: Vitamin D has significant role in dry eye disease and its inflammation. Vitamin D therapy can be considered as an added treatment for dry eye disease.

Keyword :

Dendritic cells, Vitamin D, Inflammatory cells, Dry eye.

Doi :

10.18231/2394-6377.2018.0091

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