Abstract :
Resistance to antibiotics is one of the greatest problems to the success of modern medication. Due to the emergence of multi-drug resistant bacteria, selection of effective antibiotics for suppression of microbial activity has been an incidental issue. The aim of this study is to determine the antimicrobial activities of sweet orange juice on isolated S. aureus, E. coli, Pseudomonas spp, & Klebsiella spp, which were subjected to different concentrations of sweet orange juice to determine their response to the juice concentrations. 25%, 50%, & 100% concentrations were used respectively using a well-in-agar diffusion method and it was discovered that all the microorganisms were sensitive to the sweet orange juice at 100% concentration only with zones of inhibitions as follows: Staphylococcus aureus (4mm), E.coli (1mm), Klebsiella spp (1mm), & Pseudomonas spp (2mm). This shows that the juice cannot be recommended as alternative for antibiotics development since it only inhibited the microbial growth at 100% concentration only, and its respective zones of inhibition were minimal or less effective.
Keyword :
Antibacterial susceptibility, Citrus sinensis (Sweet Orange) juice.