A BRIEF REVIEW OF POLYELECTROLYTE COMPLEX: AN UPDATE


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Volume :

4

Issue :

4

Abstract :

This review work gives a lot of information on polyelectrolyte complexes (PECs). These complexes used in different dosage forms for the formulation of stable aggregated macromolecules. In the current scenario, polymers as carrier have revolutionized the drug delivery system. These PECs avoid the use of different chemical agents, thus reduce the risk of toxicity. By introducing polyelectrolyte many properties like viscosity, polarizability, diffusion coefficient, chain conformation, miscibility etc., are significantly changed due to the introduction of a polyelectrolyte. The PECs influenced not only by chemical properties like molecular weight, stereochemistry, charge density, etc. Polyelectrolyte complex prolong the therapeutic action by delivering drug target sties, sustained and controlled release rate of the drug by acting as carrier. Thus, the present review focuses on polyelectrolyte complex and their method of preparation.

Keyword :

Polyelectrolyte complexes, viscosity, polarizability, diffusion coefficient, chain conformation and miscibility
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