Abstract :
Two novel 2 substituted benzimidazole derivatives were synthesized from 2 chloromethyl 1H benzimidazole and 2 2 chlorophenyl 1H benzo d imidazole with 1H 1,2,4 triazol 3 amine. Their structures were characterized by Infrared spectroscopy, Nuclear magnetic resonance, 1H, 13C , Elemental analysis. Density functional theory DFT studies were performed using the B3LYP 6 31G d, p basis set to expand imminent into their structural properties. All the synthesized compounds were screened for antimicrobial activity against a panel of selected bacterial and fungal strains using ciprofloxacin and fluconazole as standards. C. M. Mahalakshmi "Synthesis, Spectral Analysis, DFT and Antimicrobial of Some Novel Benzimidazole Derivatives" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-4 , June 2018, URL: https://www.ijtsrd.com/papers/ijtsrd14595.pdf Paper URL: http://www.ijtsrd.com/chemistry/other/14595/synthesis-spectral-analysis-dft-and-antimicrobial-of-some-novel-benzimidazole-derivatives/c-m-mahalakshmi
Keyword :
2-chloromethyl-1H-benzimidazole,2-(2-chlorophenyl)-1H-benzo[d]imidazole, 1H-1,2,4-triazol-3-amine , IR & NMR spectral data, DFT and Antimicrobial efficiency