Abstract :
Background: Atherosclerosis leading to ischemic heart disease remains the major cause of death and premature disability
in developed countries and its prevalence is rising constantly in developing countries. Dyslipidaemia due to insulin
resistance, the major cause of coronary atherosclerosis and ischemic heart disease is frequently associated with type 2
diabetes mellitus. Type 2 diabetes mellitus is an emerging pandemic with the number of patients increasing rapidly in both
developed and developing countries around the world. Methods: In this study lipid abnormalities associated with type 2
diabetes mellitus were studied and association between HbA1C level and extent of dyslipidaemia detected. In this crosssectional
study 100 known cases of type 2 diabetes mellitus will be selected. They will be investigated for HbA1C and lipid
profile. The data obtained will be analyzed by appropriate statistical methods. Results: In the present study, dyslipidaemia
was found to be present in 89% patients of type 2 diabetes mellitus. Of these, 21% had single abnormal lipid parameter
while 68% had combined dyslipidaemia. There was highly significant correlation between HbA1C & total cholesterol,
HbA1C & LDL cholesterol, HbA1C & triglycerides, HbA1C & Tc/HDL ratio and HbA1C & non HDL cholesterol. Also, highly
significant inverse correlation between HbA1C & HDL cholesterol was found. Conclusion: Prevalence of dyslipidaemia
was alarmingly high in type 2 diabetes mellitus patients. Thus, HbA1C can be considered as a marker of dyslipidaemia in
type 2 diabetes mellitus.
Keyword :
Dyslipidaemia, Type 2 Diabetes Mellitus, Correlation, Risk factor.