Abstract :
Perioperative blood loss is one of the modifiable factors that have been in focus during the last decade. Major
orthopaedic surgeries are associated with significant amount of blood loss in the intra and post operative period
.The purpose of reducing the perioperative blood loss protocol is to decrease the need of allogenic blood
transfusions and eliminate the transfusion related complications. The protocol can be divided into pre operative
risk assessment, pre operative preparation, optimizing the operative technique and post operative management.
The strategies used during these periods can decrease the peri operative blood loss. Traneaxaemic acids is the
most promising agent in this regard by its virtues of cost effectiveness, ease of availability and administration and
without increase in the risk of thromboembolic events. Decreased peri operative blood loss translates into
reduced need of blood transfusions, better recovery, decreased rate of complications and reduced economic
burden.
Keyword :
Peri operative blood loss, Tranexaemic acid, Bipolar tissue sealants, Fibrin sealants, Post operative blood transfusions.