MicroRNA Disease Predictions Based On Genomic Data


Article PDF :

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Article type :

Original Article

Author :

Ajitha. C | DivyaLakshmi. K | Jothi Jayashree. M

Volume :

2

Issue :

3

Abstract :

Gene Ontology is a structured library of concepts related with one or more gene products through a process called annotation. Association Rules that discovers biologically relevant and corresponding associations. In the existing system, they used Gene Ontology based Weighted Association Rules for extracting annotated datasets. We here adapt the MOAL algorithm to mine cross ontology association rules. Cross ontology rules to manipulate the Protein values from three sub ontologys for identifying the gene attacked disease. It focused on intrinsic and extrinsic values. The Co Regulatory modules between microRNA, Transcription Factor and gene on function level with multiple genomic data. The regulations are compared with the help of integration technique. Iterative Multiplicative Updating Algorithm is used in our project to solve the optimization module function for the above interactions. Comparing the regulatory modules and protein value for gene and generating Bayesian rose tree for the efficiency of our result. Ajitha. C | DivyaLakshmi. K | Jothi Jayashree. M "MicroRNA-Disease Predictions Based On Genomic Data" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-2 | Issue-3 , April 2018, URL: https://www.ijtsrd.com/papers/ijtsrd11386.pdf Paper URL: http://www.ijtsrd.com/computer-science/data-miining/11386/microrna-disease-predictions-based-on-genomic-data/ajitha-c

Keyword :

microRNA(miRNA), transcription factor, co-regulatory module, genomic data, mining algorithm
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