Abstract :
Aim: To compare the clinical and the histopathological outcomes of fibrin glue versus vicryl sutures for fixing amniotic membrane grafts in patients undergoing pterygium excision.
Methods: The study was a randomized control study involving thirty patients with primary pterygium. All underwent pterygium surgery with amniotic membrane graft and every alternate patient had the graft secured with fibrin glue and 8 ‘0’ vicryl sutures. Therefore 15 eyes had the grafts attached with fibrin glue and 15 eyes had it attached with 8 ‘0’ vicryl suture in the recipient site. The patients were examined on 1st, 15th and 45th day to assess the patients comfort, duration of surgery, position of the graft and the histopathological examination of the edge of tissues on 1st and 15th day.
Results: Our results showed that amniotic membrane grafts are an effective alternative for conjunctival autografts in pterygium excision surgery in reducing inflammation and recurrence. The use of fibrin glue in attaching amniotic membrane grafts significantly reduces surgery time, improves post-operative patient comfort and results in decreased inflammation with faster healing
Keyword :
Pterygium, Amniotic membrane graft, Fibrin glue, vicryl suture, Histology