Abstract :
Background: Thyroid hormone play important role in development of Central Nervous System and in myelination of
neurons. Patients of hypothyroidism may suffer from peripheral nervous dysfunction. Aim of our study is to find out the
neuropathy in hypothyroidism. Methods: MNCV and latency of Median, Ulnar, and Common Peroneal nerve of both upper
and lower limb were done in patients of Hypothyroidism and in Control subjects. Results: Significant bilateral decrease is
observed in the MNCV of the Median Nerve in Hypothyroid subjects as compared to the control subjects. Also there is
Significant bilateral increase in the Motor Latency of the Median Nerve in Hypothyroid subjects as compared to the control
subjects. Conclusion: Hypothyroidism cause significant decrease in MNCV of Median Nerve as well as increase in Motor
latency in Median Nerve.
Keyword :
Hypothyroidism, Nerve Conduction Study, Neuropathy.